Single-use Bioreactors Market by Product (Single-use Bioreactor, Media Bags, Filtration Assembly, Others), Usage (Lab-scale, Pilot Scale, Large-scale), Type (Stirred tank, Wave-Induced, Bubble-Column, Others), Cell Type (Mammalian, bacterial, Yeast, Others), Application (Bioproduction, Research, Process Development), End user (Pharma and Biotech, CROs, Research and Academia) - Global Forecast to 2025

The single-use bioreactor market will increase at a CAGR of 21.6% from 2019 to 2025 to reach $3.37 billion by 2025. Single-use bioreactor utilizes disposable bag instead of reusable steel vessel used in conventional bioreactors. The use of single‑use bioreactor is influenced by the criticality of the step, fully automated technology, the value of the product produced, and the time taken for product development and production. Owing to the factors such as rapid adoption of disposable technology in pharmaceutical and biotechnology industry, cost effectiveness and lower downtime of single-use bioreactor, increase in government support for biopharmaceutical research, growing demand for biopharmaceuticals, and frequent launch of new products, this industry has witnessed a steady growth.

Furthermore, significant opportunities from emerging economies, demand for personalized medicine, and expected surge in biosimilar production in U.S. is expected to boost the growth of single-use bioreactor market in near future. For instance, according to PharmaManufacturing.com (e-magazine), ~$110 billion of biologics are expected to become off-patent by 2020. Hence, with the growing pressure to reduce the healthcare cost and regulatory clarity on biosimilar, the demand for biosimilars is likely to increase in coming years. Similarly, the increase in number of commercially available personalized medicine in the market from 5 in 2008 to 132 in number in 2016, is boosting the market with the similar trend.

Analysis of Market Segments

The global single-use bioreactor market is segmented by product (single-use bioreactor systems, media bags, filtration assemblies, and others), by molecule type (vaccines, monoclonal antibodies, stem cells, recombinant proteins, drugs, and others), type (stirred-tank, wave-induced, bubble-column, and others), cell type (mammalian, bacterial, yeast, and others), by application (bio production, research, and process development), usage (lab-scale, pilot-scale, large-scale), and end user (pharmaceutical & biotechnology company, contract research organizations research & academia), and geography.

Based on usage, lab-scale production is the most common setting in which single-use bioreactors are preferably used. Lab-scale production commanded the largest share of the global single-use bioreactor market in 2018, owing to simple operation, limited sterilization requirements, and reduced chances of cross-contamination.

Based on application, bio production commanded the largest market share of the global single-use bioreactor market. The high market share of this segment is due to growing demand for breakthrough therapies; increasing government funding; and growing research programs for biopharmaceutical production.

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Key Players

The report includes competitive landscape based on extensive assessment of the key strategic developments adopted by the leading market participants in the industry over the past 5 years (2015-2018). The key players profiled in the global single-use bioreactor market research report are GE Healthcare, Merck Group, Danaher Corporation, Sartorius AG, Thermo Fisher Scientific Inc., Eppendorf AG, Applikon Biotechnology B.V., Solaris Biotechnology SRL, Cellexus Ltd, CESCO Bioengineering Co., Ltd., PBS Biotech, Inc., Pierre Guerin Technologies, Distek, Inc., Parker-Hannifin Corporation, Celltainer Biotech B.V., and Infors AG.

Future Outlook

Growing adoption of single-use technology since the past decade has been gaining traction at a fast pace and it is expected that most of the biopharmaceutical manufacturers will be having 100% fully disposables facility in operation in the coming years. In these facilities, the major device will be disposable bioreactors, with highest number of installations. Also, these bioreactors will be embedded with improved sensors and higher operational flexibility for multi-drug production within less time. Further, high capacity disposable bioreactors are expected to replace conventional bioreactors in large-scale manufacturing facilities.

Single-use Bioreactors Market Segmentation:

Single-use Bioreactors Products

• Single-use Bioreactor systems
  • Up to 10L
  • 11-100L
  • 101-500L
  • 501-1500L
  • Above 1500L
• Media bags
• Filtration Assemblies
• Others

Single-use Bioreactors Molecules

• Vaccines
• Monoclonal Antibodies
• Stem Cells
• Recombinant Proteins
• Drugs
• Others

Single-use Bioreactors Types

• Stirred-Tank
• Wave-Induced
• Bubble-Column
• Others

Single-use Bioreactors for Cell Types

• Mammalian cells
• Bacterial cells
• Yeast cells
• Others

Single-use Bioreactors Applications

• Bioproduction
• Research and development
• Process development

Single-use Bioreactors Usages

• Lab-scale Production
• Pilot-scale Production
• Large-scale Production

Single-use Bioreactors End users

• Pharmaceutical & Biotechnology companies
• Contract Research Organizations (CROs)
• Research and Academia

Single-use Bioreactors Segmentation by Geography

• North America
  • U.S.
  • Canada
• Europe
  • Germany
  • France
  • U.K.
  • Italy
  • Spain
  • Rest of Europe
• Asia-Pacific
  • Japan
  • China
  • India
  • Rest of Asia-Pacific
• Rest of the World
  • Latin America
  • Middle East & Africa

Key players of the Single-use Bioreactors Market

• GE Healthcare
• Merck Group
• Danaher Corporation
• Sartorius AG
• Thermo Fisher Scientific Inc.
• Eppendorf AG
• Applikon Biotechnology B.V.
• Solaris Biotechnology SRL
• Cellexus Ltd
• CESCO Bioengineering Co., Ltd.
• PBS Biotech, Inc.
• Pierre Guerin Technologies
• Distek, Inc.
• Parker-Hannifin Corporation,
• Celltainer Biotech B.V.
• Infors AG.

Key questions answered in the report:

Pharmaceutical & biotechnology companies accounted for the largest share of the single-use bioreactor market, globally

• Which geographic region is expected to experience the fastest growth in the usage of single-use bioreactor in pharmaceutical & biotechnology companies?
• How does the penetration of single-use bioreactor in pharmaceutical & biotechnology companies differ from other end users such as contract research organizations and research and academia?

Single-use bioreactor market favors both larger and local manufacturers that compete in multiple segments

• Who are the top competitors in this market and what strategies do they employ to gain shares?
• What is driving growth and which market segments have the most potential for revenue expansion over the forecast period?
• What strategies should new companies look to enter this market use to compete effectively?
• What are the major drivers, restraints, challenges, and opportunities in the single-use bioreactor market?
• Who are the major players in various countries and what share of the market do they hold?
• What are the geographical trends and high growth regions/ countries?

Recent partnerships, acquisitions, and expansions have taken place in the global single-use bioreactor market

• Which companies have recently merged/acquired and how will these unions affect the competitive landscape of the single-use bioreactor market?
• Which companies have created partnerships and how will these partnerships promote a competitive advantage?
• Who are the major players in the global single-use bioreactor market and what share of the market do they hold?
• What are the local emerging players in the global single-use bioreactor market and how do they compete with the global players?