In-Vitro Toxicology/Toxicity Testing Market by Product and Service, Technology (Cell Culture, OMICS), Method (Cell-based Assays, In-Silico), End-point (ADME, Genotoxicity, Organ Toxicity, Dermal Toxicity), End-user, and Geography – Global Forecast to 2025

  • Report ID:MRHC - 104348
  • Pages: 189
  • Nov 2019
  • Formats*: PDF
  • Category: Healthcare

1. Introduction 
    1.1. Market Definition 
    1.2. Market Segmentation 
    1.3. Currency 
    1.4. Limitations 
    1.5. Key Stakeholders 

2. Research Methodology 
    2.1. Research Process 
           2.1.1. Secondary Research 
           2.1.2. Primary Research 
           2.1.3. Market Size Estimation

3. Executive Summary 
    3.1. Introduction 
    3.2. Market Dynamics 
    3.3. Market Assessment, by Product 
    3.4. Market Assessment, by Technology 
    3.5. Market Assessment, by Method 
    3.6. Market Assessment, by End Point 
    3.7. Market Assessment, by End User 
    3.8. Regional Analysis 
    3.9. Competitive Analysis 

4. Market Insights 
    4.1. Introduction 
    4.2. Drivers 
           4.2.1. Ban on Animal Testing for Cosmetics 
           4.2.2. Need to Develop Early Toxicology Testing Methods 
           4.2.3. Advancements in In Vitro Methodologies 
           4.2.4. Low Cost Associated with In Vitro Methodologies 
    4.3. Restraints 
           4.3.1. Failure to Establish Intricacies of In Vivo Conditions 
           4.3.2. Limited In Vitro Models to Test Complex Endpoints 
    4.4. Opportunities 
           4.4.1. Synergistic Relationships between Industry Stakeholders 
           4.4.2. Increasing Toxicology Databases 
    4.5. Regulatory Agencies 

5. In Vitro Toxicology Testing Market, by Product and Service 
    5.1. Introduction 
    5.2. Equipment 
    5.3. Assay Kits 
    5.4. Consumables 
    5.5. Software 
    5.6. Services 

6. In Vitro Toxicology Testing Market, by Technology 
    6.1. Introduction 
    6.2. Cell Culture Technologies 
    6.3. High-Throughput Screening Technologies 
    6.4. Omics Technologies 

7. In Vitro Toxicology Testing Market, by Method 
    7.1. Introduction 
    7.2. Cell-Based Assays 
    7.3. Biochemical Assays 
    7.4. In-Silico 
    7.5. Ex-Vivo 

8. In Vitro Toxicology Testing Market, by End Point 
    8.1. Introduction 
    8.2. ADME (Absorption, Distribution, Metabolism, Excretion) 
    8.3. Skin Irritation, Corrosion, & Sensitization 
    8.4. Genotoxicity 
    8.5. Cytotoxicity 
    8.6. Ocular Toxicity 
    8.7. Organ Toxicity 
    8.8. Phototoxicity 
    8.9. Dermal Toxicity 
    8.10. Other Toxicity End Points 

9. In Vitro Toxicology Testing Market, by End User 
    9.1. Introduction 
    9.2. Pharmaceutical and Biotechnology Industry 
    9.3. Cosmetics Industry 
    9.4. Food Industry 
    9.5. Chemical Industry 

10. Geographic Analysis 
       10.1. Introduction 
       10.2. Europe 
               10.2.1. Germany 
               10.2.2. U.K. 
               10.2.3. France 
               10.2.4. Italy 
               10.2.5. Spain 
               10.2.6. Rest of Europe 
       10.3. North America 
               10.3.1. U.S. 
               10.3.2. Canada 
        10.4. Asia Pacific 
                 10.4.1. China 
                 10.4.2. Japan 
                 10.4.3. India 
                 10.4.4. RoAPAC 
         10.5. Latin America 
         10.6. Middle East and Africa 

11. Competitive Landscape 
       11.1. Competitive Growth Strategies 
       11.2. Market Share Analysis 
               11.2.1. Thermo Fisher Scientific 
               11.2.2. Merck KgaA 
               11.2.3. GE Healthcare 

12. Company Profiles (Business Overview, Financials, Product Portfolio, Business Strategies, Recent Developments)
         12.1. SGS S.A. 
         12.2. Covance, Inc. (A Part of Laboratory Corporation of America Holding) 
         12.3. Bio-Rad Laboratories, Inc. 
         12.4. Qiagen N.V. 
         12.5. GE Healthcare 
         12.6. Eurofins Scientific  
         12.7. Merck KgaA 
         12.8. Thermo Fisher Scientific, Inc. 
         12.9. Charles River Laboratories International, Inc. 
         12.10. Catalent, Inc.   

List of Tables

Table 1 Currency Conversion Rates for USD 
Table 1 Cost Comparison: In Vivo vs In Vitro 
Table 2 In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 3 In Vitro Toxicology Testing Equipment Market, by Country/Region, 2017–2025 ($ Million)
Table 4 In Vitro Toxicology Testing Assay Kits Market, by Country/Region, 2017–2025 ($ Million) 
Table 5 In Vitro Toxicology Testing Consumables Market, by Country/Region, 2017–2025 ($ Million)
Table 6 In Vitro Toxicology Testing Software Market, by Country/Region, 2017–2025 ($ Million) 
Table 7 In Vitro Toxicology Testing Services Market, by Country/Region, 2017–2025 ($ Million) 
Table 8 In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 9 Cell Culture Technologies Market For In Vitro Toxicology Testing, by Country/Region, 2017–2025 ($ Million) 
Table 10 High Throughput Technologies Market For In Vitro Toxicology Testing, by Country/Region, 2017–2025 ($ Million) 
Table 11 Omics Technologies Market For In Vitro Toxicology Testing, by Country/Region, 2017–2025 ($ Million) 
Table 12 In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 13 Cell-Based Assays Market For In Vitro Toxicology Testing, by Country/Region, 2017–2025 ($ Million) 
Table 14 Biochemical Assays Market For In Vitro Toxicology Testing, by Country/Region, 2017–2025 ($ Million) 
Table 15 In Silico Testing Market For In Vitro Toxicology Testing, by Country/Region, 2017–2025 ($ Million) 
Table 16 Ex Vivo Testing Market For In Vitro Toxicology Testing, by Country/Region, 2017–2025 ($ Million) 
Table 17 In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 18 In Vitro ADME Testing Market, by Country/Region, 2017–2025 ($ Million) 
Table 19 In Vitro Skin Irritation, Sensitization & Corrosion Testing Market, by Country/Region, 2017–2025 ($ Million) 
Table 20 In Vitro Genotoxicity Testing Market, by Country/Region, 2017–2025 ($ Million) 
Table 21 In Vitro Cytotoxicity Testing Market, by Country/Region, 2017–2025 ($ Million) 
Table 22 In Vitro Ocular Toxicity Testing Market, by Country/Region, 2017–2025 ($ Million)
Table 23 In Vitro Organ Toxicity Testing Market, by Country/Region, 2017–2025 ($ Million)
Table 24 In Vitro Phototoxicity Testing Market, by Country/Region, 2017–2025 ($ Million) 
Table 25 In Vitro Dermal Toxicity Testing Market, by Country/Region, 2017–2025 ($ Million)
Table 26 In Vitro Other Toxicity Testing Market, by Country/Region, 2017–2025 ($ Million)
Table 27 In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 28 In Vitro Toxicology Testing Market For Pharmaceutical And Biotechnology Industry, by Country/Region, 2017–2025 ($ Million) 
Table 29 In Vitro Toxicology Testing Market For Cosmetic Industry, by Country/Region, 2017–2025 ($ Million) 
Table 30 In Vitro Toxicology Testing Market For Food Industry, by Country/Region, 2017–2025 ($ Million) 
Table 31 In Vitro Toxicology Testing Market For Chemical Industry, by Country/Region, 2017–2025 ($ Million) 
Table 32 Global In Vitro Toxicology Testing Market, by Country/Region, 2017–2025 ($ Million)
Table 33 Europe: In Vitro Toxicology Testing Market, by Country/Region, 2017–2025 ($ Million) 
Table 34 Europe: In Vitro Toxicology Testing Market, by Product And Service, 2017–2025 ($ Million) 
Table 35 Europe: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million)
Table 36 Europe: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 37 Europe: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 38 Europe: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 39 Germany: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 40 Germany: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million)
Table 41 Germany: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 42 Germany: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million)
Table 43 Germany: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million)
Table 44 U.K.: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 45 U.K.: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 46 U.K.: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 47 U.K.: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 48 U.K.: In Vitro Toxicology Testing Market, by End User 2017–2025 ($ Million) 
Table 49 France: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 50 France: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million)
Table 51 France: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 52 France: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 53 France: In Vitro Toxicology Testing Market, by End User 2017–2025 ($ Million) 
Table 54 Italy: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 55 Italy: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 56 Italy: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 57 Italy: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 58 Italy: In Vitro Toxicology Testing Market, by End User 2017–2025 ($ Million) 
Table 59 Spain: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 60 Spain: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 61 Spain: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 62 Spain: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 63 Spain: In Vitro Toxicology Testing Market, by End User 2017–2025 ($ Million) 
Table 64 RoE: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 65 RoE: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 66 RoE: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 67 RoE: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 68 RoE: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 69 North America: In Vitro Toxicology Testing Market, by Country/Region, 2017–2025 ($ Million) 
Table 70 North America: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 71 North America: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 72 North America: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 73 North America: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 74 North America: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 75 U.S.: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 76 U.S.: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 77 U.S.: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 78 U.S.: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 79 U.S.: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 80 Canada: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 81 Canada: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million)
Table 82 Canada: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 83 Canada: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 84 Canada: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 85 Asia Pacific: In Vitro Toxicology Testing Market, by Country, 2017–2025 ($ Million)
Table 86 Asia Pacific: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 87 Asia Pacific: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 88 Asia Pacific: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million)
Table 89 Asia Pacific: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 90 Asia Pacific: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million)
Table 91 China: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 92 China: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 93 China: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 94 China: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 95 China: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 96 Japan: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 97 Japan: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 98 Japan: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 99 Japan: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 100 Japan: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 101 India: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 102 India: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 103 India: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 104 India: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 105 India: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 106 RoAPAC: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 107 RoAPAC: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million)
Table 108 RoAPAC: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 109 RoAPAC: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 110 RoAPAC: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 111 LATAM: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 112 LATAM: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) Table 113 LATAM: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 114 LATAM: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 115 LATAM: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 
Table 116 MEA: In Vitro Toxicology Testing Market, by Product and Service, 2017–2025 ($ Million) 
Table 117 MEA: In Vitro Toxicology Testing Market, by Technology, 2017–2025 ($ Million) 
Table 118 MEA: In Vitro Toxicology Testing Market, by Method, 2017–2025 ($ Million) 
Table 119 MEA: In Vitro Toxicology Testing Market, by End Point, 2017–2025 ($ Million) 
Table 120 MEA: In Vitro Toxicology Testing Market, by End User, 2017–2025 ($ Million) 

List of figures

Figure 1 Research Process 
Figure 2 Key Executives Interviewed 
Figure 3 Primary Research Techniques 
Figure 4 Market Size Estimation 
Figure 5 Global In Vitro Toxicology Testing Market, 2017–2025 ($Million) 
Figure 6 In Vitro Toxicology Testing: Global Market Outlook, by Product And Service 2019 Vs. 2025
Figure 7 In Vitro Toxicology Testing: Global Market Outlook, by Technology 2019 Vs. 2025 
Figure 8 In Vitro Toxicology Testing: Global Market Outlook, by Method 2019 Vs. 2025 
Figure 9 In Vitro Toxicology Testing: Global Market Outlook, by End Point 
Figure 10 In Vitro Toxicology Testing: Global Market Outlook, by End User 
Figure 11 In Vitro Toxicology Testing: Regional Market Outlook 
Figure 12 Market Dynamics 
Figure 13 In Vitro Toxicology Testing Market, by Product And Service, 2019 Vs. 2025 ($ Million)
Figure 14 In Vitro Toxicology Testing Market, by Technology, 2019 Vs. 2025 ($ Million) 
Figure 15 In Vitro Toxicology Testing Market, by Method, 2019 Vs. 2025 ($ Million) 
Figure 16 In Vitro Toxicology Testing Market, by End Point, 2019 Vs. 2025 ($ Million) 
Figure 17 In Vitro Toxicology Testing Market, by End User, 2019 Vs. 2025 ($ Million) 
Figure 18 In Vitro Toxicology Testing Market, by Region, 2019 Vs. 2025 ($ Million) 
Figure 19 Growth Strategies Adopted by Key Players (2016-2019) 
Figure 20 Market Share Analysis for In Vitro Toxicity Testing Market (Excluding Services), 2018
Figure 21 SGS S.A.: Financial Overview 
Figure 22 Covance, Inc.: Financial Overview 
Figure 23 Bio-Rad Laboratories, Inc.: Financial Overview 
Figure 24 Qiagen N.V.: Financial Overview 
Figure 25 GE Healthcare: Financial Overview 
Figure 26 Eurofins Scientific Se: Financial Overview 
Figure 27 Merck KgaA: Financial Overview 
Figure 28 Thermo Fisher Scientific, Inc.: Financial Overview 
Figure 29 Charles River Laboratories International, Inc.: Financial Overview 
Figure 30 Catalent, Inc.: Financial Overview

The global in-vitro toxicology testing market is expected to grow at a CAGR of 9% from 2019 to reach $14.4 billion by 2025. Factors such as ethical issues and pressure from animal activists’ groups concerning the use of animals for testing, ban on animal testing on cosmetic products, support from regulatory bodies regarding the approval of in-vitro tests, low costs associated with in-vitro toxicology testing, and advancements in in-vitro methodologies are driving the growth of the overall in-vitro toxicology market. Synergetic relationships between various stakeholders of the industry and increasing toxicology databases to facilitate the use of in-vitro test methods are further expected to offer significant growth opportunities for the players operating in this market. Regulatory bodies such as ICCVAM, ECVAM, JaCVAM, and OECD have already approved and validated more than 60 in vitro toxicology tests.

Ban on Animal Testing for Cosmetics Fuels the Growth of the Global In-Vitro Toxicology Testing Market

In 2004, the EU passed a legislation prohibiting the use of finished cosmetic products on animals. In 2009, the testing of cometic ingredients on animals was prohibited within the EU. This was further ammended by forbidding the marketing of cosmetic products tested on animals from March 2013. Complex toxicity end-points such as repeated dose toxicity, reproductive toxicity, and toxicokinetics were exempted from this ban. Other similar initiatives taken by various governments are as below:

  • In 2014, the Chinese government put an end to mandatory testing of cosmetics on animals; and increased the research into alternative methods for animal testing.
  • In January 2014, the Ministry of Health and Family Welfare published draft ammendment seeking a ban on testing on cosmetics to the Drugs and Cosmetics rule in the Gazzette of India
  • In 2015, India became the first South-Asian country to ban import of animal-tested beauty products
  • In 2015, New Zealand government announced a ban on animal testing on cosmetics.
  • The U.S. introduced the Humane Cosmetics Act to ban animal testing on cosmetics in 2015
  • In March 2015, the U.K. government announced complete ban on testing of household products on animals which came into effect from October 2015
  • In November 2015, the UK implemented ban on marketing on household products tested on animals
  • In December 2016, the Swiss government banned the sale of cosmetics containing ingredients tested on animals
  • In March 2016, Russia introduced a bill to replace all animal testing on cosmetics and ingredients by 2020.
  • In July 2017, Australia imposed a testing and marketing ban on cosmetics tested on animals.

In 2013, The Humane Society of the United States (HSUS) and Humane Society International launched a global campaign “Be Cruelty-Free” in agreement with the EU ban on selling animal tested cosmetics. The HSUS and Humane Society Legislative Fund are partnering with scientists, government officials, and industry leaders to make the U.S. the next biggest cruelty-free nation. Such initiatives by various governments to ban the use of animals for cosmetics testing are contributing to the increasing adoption of in vitro toxicology tests.

In Vitro Toxicology/ Toxicity Testing Market

Click here to: Get Free Sample Pages of this Report

Need to Develop Early Toxicology Testing Methods Supports the Market Growth

Drug development is always associated with the highest risk of failure in the later stages where the capital at stake is high. Toxicity testing accounts for ~30% of expensive, late-stage failures in drug development and market withdrawal, which may result in high attrition rate in the late-stages of the pharmaceutical drug discovery process. According to NCBI, for every 10,000 compounds synthesized in the discovery phase, only 250 reach the preclinical phase, ultimately resulting in one approved drug by the FDA. Therefore, to lower the risk of the same, it is very important to identify and prioritize efforts to bring the attrition of failing molecules at an early stage in drug development. According to the CMR International, 22% of the drug candidates that entered clinical development from 2006 to 2012 failed due to non-clinical toxicology or clinical safety issues. In preclinical development, toxicity and safety issues accounted for 54% of failures (18% of all preclinical candidates). These expensive late-stage failures account for a large proportion of the pharmaceutical R&D cost, and is estimated to be USD 1.8 billion per marketed drug.

The industry is seeking additional efficiencies in preclinical R&D by identifying solutions in the discovery phase to better qualify new molecular entities prior to animal and human testing. The goal of the new R&D model is to increase the chances of a phase I candidate to reach approval by increasing the rigor of qualifying compounds in the preclinical stages. In order to facilitate this, research is increasing in early stages, which is in turn driving the growth of in-vitro toxicology testing market. As the evolving technologies of in-vitro screening and modeling, various in-vitro assays are emerging as a rapid, high-efficient and cost-effective choice of estimating drug safety risks recommended by most regulatory authorities. In May 2019, Scientists in the Department of Biosystems Science and Engineering at ETH Zurich in Basel have now developed a test that allows them to examine a drug's embryotoxicity in cell cultures instead of animals. This new procedure is simple, fast, and inexpensive, enabling researchers to use it to test a large number of drug candidates at an early drug development stage.

Low Cost Associated with In-Vitro Methodologies is Catching the Attention

Animal tests are very expensive and time consuming. It can take anything from a few months to 4-5 years to conduct in-vivo toxicology, and can cost hundreds of thousands—and sometimes millions—of dollars per substance examined. In spite of such huge expenditure, many drugs fail at later stages of drug discovery phases. The inefficiency and exorbitant costs associated with animal testing makes it impossible for regulators to adequately evaluate the potential effects of more than 100 thousand chemicals. In contrast, in vitro methods are amenable to high throughput automation using robotics at a much lower cost than animal tests.

Key Findings in the Global In-Vitro Toxicology Testing Market Study:

OMICS Technologies to Post the Fastest Growth

OMICS technologies aim to understand and predict toxicity by using omics data in order to study systems-level responses. Recent years have witnessed a rapid increase in publicly available omics data, particularly gene expression data, and a corresponding development of methods for toxicological analysis. The application of omics-based technologies in toxicological research has the potential to provide tools to tackle uncertainties from in-vivo toxicological evaluations. As gene expression rapidly changes in response to toxic exposure, it can be used as a sensitive endpoint.

Cell-based Assays Dominates the Global In-Vitro Toxicology Testing Market

The cell-based assays segment is estimated to account for the largest share of the overall in-vitro toxicology testing market in 2019. Cell-based assays help detect and measure cell viability, functionality, and growth. This method of toxicity detection is faster, more effective, and less expensive as compared to biochemical and ex vivo methods. These assays allow integration of targets and pathways in a more physiological setting as compared to biochemical assays. Advancements in cell-based technologies such as high-content screening and label-free detection are expected to further drive the market growth for cell-based assays.

Cosmetics Industry to Witness the Fastest Growth through 2025

The increasing use of cosmetics owing to the rising disposable incomes and their easy availability to the public has driven the industry to invest in the research of breakthrough products and develop human safe products. The subsequent rise in the animal testing of cosmetics and household products during the 1980s and 1990s, especially in the EU, has stimulated the regulatory authorities to enforce strict laws that ban animal testing of these products. Additionally, the demand for cruelty-free cosmetics and personal care products has skyrocketed.

Asia Pacific: The Fastest Growing Regional Market

Asia-Pacific region is expected to grow at the fastest CAGR during the forecast period of 2019 to 2025, owing to increasing biotech investments in this region and increasing collaborations between local and foreign companies. Countries like China, India, South Korea etc. are a hub for biotechnology R&D investments in this region. Many countries in this region have already banned the use of animals for toxicity testing in cosmetics, while many are considering a ban. Thus, factors such as huge R&D investments and initiatives to develop in-vitro methods are expected to boost the in-vitro toxicology testing market in this region.

Key Players

The report includes competitive landscape based on extensive assessment of the key strategic developments adopted by the leading market participants in the industry over the past 5 years (2015-2019). The key players profiled in the global in-vitro toxicology testing market research report are SGS S.A., Covance, Inc. (A Part of Laboratory Corporation of America Holding), Bio-Rad Laboratories, Inc., Qiagen N.V., GE Healthcare, Eurofins Scientific SE, Merck KGAA, Thermo Fisher Scientific, Inc., Charles River Laboratories International, Inc., and Catalent, Inc. among others.

Scope of the Report:

Market by Product & Service

  • Equipment
  • Assay Kits
  • Consumables
  • Software
  • Services

Market by Technology

  • Cell Culture Technologies
  • High-Throughput Screening Technologies
  • OMICS Technologies

Market by Method

  • Cell-based Assays
  • Biochemical Assays
  • In-Silico
  • Ex-Vivo

Market by End-point

  • ADME
  • Skin Irritation, Corrosion, Sensitization
  • Genotoxicity
  • Cytotoxicity
  • Ocular Toxicity
  • Organ Toxicity
  • Phototoxicity
  • Dermal Toxicity
  • Other Toxicity End-points

Market by End-user

  • Pharmaceutical & Biotechnology Industries
  • Cosmetics Industry
  • Food Industry
  • Chemical Industry

 Market by Geography

  • Europe
    • Germany
    • U.K.
    • France
    • Italy
    • Spain
    • Rest of Europe (RoE)
  • North America
    • U.S.
    • Canada
  • Asia-Pacific (APAC)
    • China
    • Japan
    • India
    • Rest of APAC (RoAPAC)
  • Rest of World
    • Latin America
    • Middle East and Africa

Key questions answered in the report-

Ban on animal testing for cosmetics and need to develop early toxicology testing methods will propel the in-vitro toxicology/toxicity testing Market

  • How does the ban on animal testing for cosmetics and need to develop early toxicology testing methods drive the growth of the in-vitro toxicology/toxicity testing market?
  • How advancements in in-vitro methodologies and low cost associated with in vitro methodologies bolstering the in-vitro toxicology/toxicity testing market in developing and developed regions?

Consumables segment accounted for the largest share of the in-vitro toxicology/toxicity testing market

  • What factors are contributing to the frequent growth of the consumables segment among various product and services?
  • What impact does this have on the adoption of in-vitro toxicology/toxicity testing in comparison to other segments?

The Europe in-vitro toxicology/toxicity testing market favors both larger and local manufacturers that compete in multiple segments

  • Who are the top competitors in this market and what strategies do they employ to gain shares?
  • What factors are driving growth and which market segments have the most potential for revenue expansion over the forecast period?
  • What strategies should new companies look to enter this market use to compete effectively?
  • What are the major drivers, restraints, challenges, and opportunities, in the global in-vitro toxicology/toxicity testing market?
  • Who are the major players in various countries and what share of the global market do they hold?
  • What are the geographical trends and high growth regions/countries?
This website is secure and we do not share your personal information with any third party. Privacy Policy
Tags: In Vitro Diagnostics Healthcare Medical Technologies
Download Free Sample
to