Leading Factors in Tablet Processing & Packaging Equipment Market to Watch Out for in FuturePublished On: June 8, 2017
Pharmaceutical industry has grown in leaps and bounds during the last three to four decades. Initial emphasis on validation of tablets started across the industry globally sometime in late sixties or early seventies.
Tablets are single-dose preparations intended for oral administration. Some are intended to be swallowed whole, some after being chewed and some after being crushed while some are intended to be dissolved or dispersed in water before being taken and some are intended to be retained in the mouth where the active ingredient(s) is/are liberated.Tablets contain one or more active ingredients. For modifying the behaviour of the dosage forms and the active pharmaceutical ingredient (API) in the gastrointestinal tract (GIT), colouring matter authorized by national or regional authority and flavouring agents, several excipients such as diluents, binders, disintegrating agents, glidants, lubricants are mixed in the manufacturing process. Excipients added or used in the tablet processing must be approved by national or regional authority to assure that do not affect the pharmacokinetic and pharmacodynamic properties of the tablets.
The manufacturing processes for tablets should meet the requirements of good manufacturing practices (GMP). Throughout manufacturing process, certain procedures should be validated and monitored by carrying out appropriate in-process controls. These should be designed to guarantee the effectiveness of each stage of production. In-process controls during tablet production should include the moisture content of the final lubricated blend, the size of granules, the flow of the final mixture and, where relevant, the uniformity of mass of tablet cores before coating. In-process controls during tablet production should also include the dimensions (thickness, diameter), uniformity of mass, hardness and/or crushing force, friability, disintegration or dissolution rate (for example, for modified-release tablets) of the finished dosage form.
The idea of automation has replaced traditional approach in which labour-intensive methods were used that resulted in the increase of manufacturing lead time and production cost. The formulation of solid oral dosage forms, and tablets in particular, has undergone rapid change and development over the last several decades with the emergence of pre-compression, high-speed and ultra high-speed presses with induced die feeding, automated weight-control systems, new direct compression materials, and upper punch tightness on tablet presses. Some of the newer tablet presses have tablet rejection systems that are operated by a computer. Computer-controlled tablet presses only require an operator to set up the press at the proper tablet weight and thickness (or pressure). The computer can then assume complete control of the run.
Growing ageing population, increase in chronic infectious diseases, rapid growth of pharmaceutical market, growing need of GMP compliance, and technical advancements are the prominent factors that are driving the tablet processing & packaging equipment market across the world. Moreover, growing pharmaceutical markets in emerging economies offers various opportunities for the tablet processing & packaging equipment market as the stringent regulatory follow up is the primary concern for any pharmaceutical unit. However, the growing demand for the refurbished machines, mainly by the start-up units hinders the growth of the market to some extent.
North America holds the major share in the global tablet processing & packaging equipment market, followed by Europe. However, the Asia Pacific region shows a considerable growth in the tablet processing & packaging equipment market mainly due to the rising population in India and China, increasing incidence & prevalence of various chronic & infectious diseases along with rising ageing population, and increasing focus of pharmaceutical manufacturers on opening manufacturing facilities in the region.
Some of the leading players in the global tablet processing & packaging equipment market are Robert Bosch GmbH, GEA Group, I.M.A. IndustriaMacchineAutomatiche S.p.A, IDEX Corporation, The Elizabeth Companies, LMT Group, O’Hara Technologies Inc., Key International Inc., kg-pharma GmbH & Co. KG, GROUPE BRETECHE INDUSTRIES, Charles Ross & Son Company, PRISM PHARMA MACHINERY, YENCHEN MACHINERY CO., LTD, Nicomacsrl, Kevin Process Technologies Pvt. Ltd., and Cadmach Machinery Co. Pvt. Ltd.
The Global Tablet Processing and Packaging Equipment market study published by Meticulous Research® can be accessed at: Tablet Processing & Packaging Equipment Market: Global Forecast 2017- 2022
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