3D cell culture is now being viewed as a new oncology drug discovery tool as 3D cell culture enhances physiological relevance of cell-based assays. Oncology drug discovery is an expensive process, wherein millions of dollars are spent on research and development and clinical trials. In case these drugs fail to get approved, a lot of loss has to be incurred. Standard screening procedures use animals, however the suitability of animal testing to predict the effects of a drug on human is questionable, and compound may fail during clinical trials.
Oncology drug development area is specifically benefitted by using 3D cell culture technique as traditional 2D cell culture may not accurately mimic the 3D environment in which cancer cells reside. 3D cell culture models that reproduce the natural tumor environment have great potential in making cell-based assays for anticancer drugs much more meaningful, possibly lowering the cost and time of taking a drug to market. This is expected to boost the demand for 3D cell culture market in the coming years.
Moreover, strong ethical concerns regarding the use of animals for drug testing is motivating the government and regulatory bodies around the globe to use alternative methods for animal testing. 3D cell culture based assays have the potential to replace in-vivo animal testing and provide more reliable results. 3D cultures have potential to improve cell-based drug screening and identify toxic and ineffective substances at an earlier stage of the drug discovery pipeline than animal or clinical trials. Moreover, they can reduce ethically controversial animal testing.
The key participants in the market are BD Biosciences (U.S.), Thermo Fisher Scientific (U.S.) Corning Life Sciences (U.S.), Sigma-Aldrich (U.S.), Lonza Group (Switzerland), 3D Biomatrix, Inc. (U.S.), 3D Biotek LLC (U.S.), Reinnervate Ltd.(U.K), Insphero AG (Switzerland), and Nanofiber Solutions,LLC (U.S.) among others.
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